An after-hyperpolarization of medium duration in rat hippocampal pyramidal cells.
نویسندگان
چکیده
منابع مشابه
Effect of Coenzyme Q10 (ubiquinone) on hippocampal CA1 pyramidal cells following transient global ischemia/reperfusion in male wistar rat
Ischemia/Reperfusion (I/R)-induced cerebral injury has been reported as a leading cause of deathand long-term disabilities. Hippocampus is an area which is more sensitive to be affected by I/Rand hypoxic conditions. Coenzyme Q10 is a strong antioxidant which plays a role in membranestabilization. This study aims to investigate the possible role of CoQ10 in ameliorating thehistomorphological cha...
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متن کاملKv7/KCNQ/M and HCN/h, but not KCa2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells.
In hippocampal pyramidal cells, a single action potential (AP) or a burst of APs is followed by a medium afterhyperpolarization (mAHP, lasting approximately 0.1 s). The currents underlying the mAHP are considered to regulate excitability and cause early spike frequency adaptation, thus dampening the response to sustained excitatory input relative to responses to abrupt excitation. The mAHP was ...
متن کاملPre-postnatal morphogenesis of rat hippocampal pyramidal cells.
OBJECTIVE To follow-up the morphological changes of the neuroblasts as they develop to pyramidal cell in the hippocampal cerebral cortex beginning from 15 days prenatal and ending 14 days postnatal. Particular metric and numerical estimations of the dendrites developed from these cells were carried out. METHODS Fifty pregnant rats classified into 5 groups were used to obtain 15 and 18 day emb...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1989
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1989.sp017491